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RPGRIP1L Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-RPGRIP1L-Antikörper wurde für WB, IHC, ICC und IF validiert. Er ist geeignet, RPGRIP1L in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN6264825

Kurzübersicht für RPGRIP1L Antikörper (N-Term) (ABIN6264825)

Target

Alle RPGRIP1L Antikörper anzeigen
RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Reaktivität

Human, Maus, Ratte

Wirt

  • 18
  • 1
Kaninchen

Klonalität

  • 19
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RPGRIP1L Antikörper ist unkonjugiert

Applikation

  • 19
  • 13
  • 13
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    RPGRIP1L Antibody detects endogenous levels of total RPGRIP1L.

    Homologie

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    Aufreinigung

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human RPGRIP1L, corresponding to a region within N-terminal amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C. Stable for 12 months from date of receipt.

    Haltbarkeit

    12 months
  • Target

    RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

    Andere Bezeichnung

    RPGRIP1L

    Hintergrund

    Description: Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R) (PubMed:19464661). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions, the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis (PubMed:19464661). Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins (By similarity). Involved in regulation of proteasomal activity at the primary cilium probably implicating association with PSDM2 (By similarity).

    Gene: RPGRIP1L

    Molekulargewicht

    151 kDa

    Gen-ID

    23322

    UniProt

    Q68CZ1

    Pathways

    DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA
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