Replication Protein A 30 KDa Subunit (RPA30) (Internal Region) Antikörper

Produktnummer ABIN6264810

Der Kaninchen Polyklonal anti-Replication Protein A 30 KDa Subunit Antikörper wird verwendet zum Nachweis von Replication Protein A 30 KDa Subunit in Proben von Human und Maus. Er wurde validiert für ICC, IF und WB.

Kurzübersicht für Replication Protein A 30 KDa Subunit (RPA30) (Internal Region) Antikörper (ABIN6264810)

Target: Replication Protein A 30 KDa Subunit (RPA30)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)

Produktdetails

Bindungsspezifität: Internal Region

Verwendungszweck: RPA30 Antibody

Spezifität: RPA30 Antibody detects endogenous levels of total RPA30.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RPA30, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Antigendetails

Target: Replication Protein A 30 KDa Subunit (RPA30)

Andere Bezeichnung: RPA30

Hintergrund:

Description: As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

Gene: RPA4

Molekulargewicht: 28 kDa

Gen-ID: 29935

UniProt: Q13156

Pathways: Mitotic G1-G1/S Phases, DNA Replication