Ribonuclease H1 Antikörper (Internal Region)
Kurzübersicht für Ribonuclease H1 Antikörper (Internal Region) (ABIN6264778)
Target
Alle Ribonuclease H1 (RNASEH1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - Internal Region
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Spezifität
 - RNase H1 Antibody detects endogenous levels of total RNase H1.
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Homologie
 - Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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Aufreinigung
 - The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
 - A synthesized peptide derived from human RNase H1, corresponding to a region within the internal amino acids.
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Isotyp
 - IgG
 
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Applikationshinweise
 - WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 mg/mL
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Buffer
 - Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
 - 12 months
 
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- Ribonuclease H1 (RNASEH1)
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Andere Bezeichnung
 - RNASEH1
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Hintergrund
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Description: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224).
Gene: RNASEH1
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Molekulargewicht
 - 32 kDa
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Gen-ID
 - 246243
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UniProt
 - O60930
 
Target
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