RIOK3 Antikörper (Internal Region)
-
- Target Alle RIOK3 Antikörper anzeigen
- RIOK3 (RRIO Kinase 3 (RIOK3))
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser RIOK3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- RIOK3 Antibody detects endogenous levels of total RIOK3.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RIOK3, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RIOK3 Primärantikörper
-
anti-RRIO Kinase 3 (RIOK3) (AA 1-516) antibody
RIOK3 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 4A12-1D2 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 411-516) antibodyRIOK3 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 3G11 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 1-519) antibodyRIOK3 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (C-Term) antibodyRIOK3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Hund WB Wirt: Kaninchen Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) antibodyRIOK3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 146-179) antibodyRIOK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB49659 unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 1-519) antibodyRIOK3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 200-519) antibodyRIOK3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-RRIO Kinase 3 (RIOK3) (AA 434-483) antibodyRIOK3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Hamster WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- RIOK3 (RRIO Kinase 3 (RIOK3))
- Andere Bezeichnung
- RIOK3 (RIOK3 Produkte)
- Synonyme
- SUDD antikoerper, 1200013N13Rik antikoerper, D18Ertd331e antikoerper, E130306C24Rik antikoerper, Sudd antikoerper, RIO kinase 3 antikoerper, RIO kinase 3 L homeolog antikoerper, RIOK3 antikoerper, Riok3 antikoerper, riok3.L antikoerper
- Hintergrund
-
Description: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843).
Gene: RIOK3
- Molekulargewicht
- 59 kDa
- Gen-ID
- 8780
- UniProt
- O14730
-
