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ARHGAP24 Antikörper (Internal Region)

ARHGAP24 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6264735
  • Target Alle ARHGAP24 Antikörper anzeigen
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    • 27
    • 9
    • 9
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARHGAP24 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    RHG24 Antibody detects endogenous levels of total RHG24.
    Homologie
    Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RHG24, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ARHGAP24 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Andere Bezeichnung
    ARHGAP24 (ARHGAP24 Produkte)
    Synonyme
    FILGAP antikoerper, RC-GAP72 antikoerper, RCGAP72 antikoerper, p73 antikoerper, p73RhoGAP antikoerper, 0610025G21Rik antikoerper, si:ch211-65i12.2 antikoerper, Rho GTPase activating protein 24 antikoerper, ARHGAP24 antikoerper, Arhgap24 antikoerper, arhgap24 antikoerper
    Hintergrund

    Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    Gene: ARHGAP24

    Molekulargewicht
    84 kDa
    Gen-ID
    83478
    UniProt
    Q8N264
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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