RAB43 Antikörper (Internal Region)

Produktnummer ABIN6264583

Dieses Anti-RAB43-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAB43 in WB, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für RAB43 Antikörper (Internal Region) (ABIN6264583)

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RAB43 Antikörper

Bindungsspezifität: Internal Region

Spezifität: RAB43 Antibody detects endogenous levels of total RAB43.

Homologie: Pig,Horse

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB43, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Andere Bezeichnung: RAB43

Hintergrund:

Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Gene: RAB43

Molekulargewicht: 23 kDa

Gen-ID: 339122

UniProt: Q86YS6