PRDM14 Antikörper (N-Term)

Produktnummer ABIN6264408

Der Kaninchen Polyklonal Anti-PRDM14-Antikörper wurde für WB, IHC, ELISA, IF, IP, ChIP und ICC validiert. Er ist geeignet, PRDM14 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PRDM14 Antikörper (N-Term) (ABIN6264408)

Target: PRDM14 (PR Domain Containing 14 (PRDM14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)

Produktdetails anti-PRDM14 Antikörper

Bindungsspezifität: N-Term

Spezifität: PRDM14 Antibody detects endogenous levels of total PRDM14.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PRDM14, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:20-1:100, CHIP 1:20-1:100, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PRDM14

Target: PRDM14 (PR Domain Containing 14 (PRDM14))

Andere Bezeichnung: PRDM14

Hintergrund:

Description: Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. Its association with CBFA2T2 is required for the functions in pluripotency and germ cell formation (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'.

Gene: PRDM14

Molekulargewicht: 64kDa

Gen-ID: 63978

UniProt: Q9GZV8