P4HTM Antikörper (Internal Region)
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- Target Alle P4HTM Antikörper anzeigen
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser P4HTM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- P4HTM Antibody detects endogenous levels of total P4HTM.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human P4HTM, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product P4HTM Primärantikörper
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anti-Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-563) antibody
P4HTM Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-563) antibodyP4HTM Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 215-264) antibodyP4HTM Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Schwein, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 323-372) antibodyP4HTM Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Schwein, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Andere Bezeichnung
- P4HTM (P4HTM Produkte)
- Hintergrund
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Description: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Gene: P4HTM
- Molekulargewicht
- 57 kDa
- Gen-ID
- 54681
- UniProt
- Q9NXG6
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