NUP153 Antikörper (C-Term)

Produktnummer ABIN6263773

Dieses Anti-NUP153-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NUP153 in WB, ELISA, IF und ICC. Geeignet für Human, Ratte und Maus.

Kurzübersicht für NUP153 Antikörper (C-Term) (ABIN6263773)

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP153 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-NUP153 Antikörper

Bindungsspezifität: C-Term

Spezifität: Nup153 Antibody detects endogenous levels of total Nup153.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nup153, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Andere Bezeichnung: NUP153

Hintergrund:

Description: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Gene: NUP153

Molekulargewicht: 154kDa

Gen-ID: 9972

UniProt: P49790

Pathways: Protein targeting to Nucleus