NCOR2 Antikörper (C-Term)
Kurzübersicht für NCOR2 Antikörper (C-Term) (ABIN6263545)
Target
Alle NCOR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Spezifität
- NCOR2 Antibody detects endogenous levels of total NCOR2.
-
Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Chicken,Xenopus
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human NCOR2, corresponding to a region within C-terminal amino acids.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
-
Andere Bezeichnung
- NCOR2
-
Hintergrund
-
Description: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.
Gene: NCOR2
-
Molekulargewicht
- 274 kDa
-
Gen-ID
- 9612
-
UniProt
- Q9Y618
-
Pathways
- Notch Signalweg, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
-