MBD3 Antikörper (C-Term)
Kurzübersicht für MBD3 Antikörper (C-Term) (ABIN6263149)
Target
Alle MBD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- C-Term
- 
                                            Spezifität
- MBD3 Antibody detects endogenous levels of total MBD3.
- 
                                            Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- 
                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            Immunogen
- A synthesized peptide derived from human MBD3, corresponding to a region within C-terminal amino acids.
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- WB: 1:500-1:3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            Haltbarkeit
- 12 months
 
- 
                                            
- 
    - MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- 
                                            Andere Bezeichnung
- MBD3
- 
                                            Hintergrund
- 
                        Description: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. Gene: MBD3 
- 
                                            Molekulargewicht
- 33kDa
- 
                                            Gen-ID
- 53615
- 
                                            UniProt
- O95983
- 
                                            Pathways
- Chromatin Binding
 Target
- 
                    
 
                                     
                                     
                                    