MARCH1 Antikörper (C-Term)
Kurzübersicht für MARCH1 Antikörper (C-Term) (ABIN6263124)
Target
Alle MARCH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    
- 
                                            
Bindungsspezifität
 - C-Term
 - 
                                            
Spezifität
 - MARCH1 Antibody detects endogenous levels of total MARCH1.
 - 
                                            
Homologie
 - Rabbit,Chicken
 - 
                                            
Aufreinigung
 - The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
 - 
                                            
Immunogen
 - A synthesized peptide derived from human MARCH1, corresponding to a region within C-terminal amino acids.
 - 
                                            
Isotyp
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
Applikationshinweise
 - WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
 - 
                                            
 - 
    
- 
                                            
Format
 - Liquid
 - 
                                            
Konzentration
 - 1 mg/mL
 - 
                                            
Buffer
 - Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
 - 
                                            
Konservierungsmittel
 - Sodium azide
 - 
                                            
Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
Lagerung
 - -20 °C
 - 
                                            
Informationen zur Lagerung
 - Store at -20 °C. Stable for 12 months from date of receipt.
 - 
                                            
Haltbarkeit
 - 12 months
 
 - 
                                            
 - 
    
- MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
 - 
                                            
Andere Bezeichnung
 - MARCH1
 - 
                                            
Hintergrund
 - 
                        
Description: E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.
Gene: 1-Mar
 - 
                                            
Molekulargewicht
 - 32 kDa
 - 
                                            
Gen-ID
 - 55016
 - 
                                            
UniProt
 - Q8TCQ1
 
Target
 -