Melanoma Antigen Family D, 4 (MAGED4) (N-Term) Antikörper
Kurzübersicht für Melanoma Antigen Family D, 4 (MAGED4) (N-Term) Antikörper (ABIN6263074)
Target
Alle Melanoma Antigen Family D, 4 (MAGED4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Verwendungszweck
- MAGE 1 Antibody
-
Spezifität
- MAGE 1 Antibody detects endogenous levels of total MAGE 1.
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human MAGE 1, corresponding to a region within N-terminal amino acids.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- Melanoma Antigen Family D, 4 (MAGED4)
-
Andere Bezeichnung
- MAGE 1
-
Hintergrund
-
Description: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Gene: MAGEA1
-
Molekulargewicht
- 48 kDa
-
Gen-ID
- 4100
-
UniProt
- P43355
Target
-