ITGA3 Antikörper
Kurzübersicht für ITGA3 Antikörper (ABIN6262608)
Target
Alle ITGA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Integrin α3 (CD49c) Antibody detects endogenous levels of total Integrin α3 (CD49c)
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Integrin alpha3 (CD49c)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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Andere Bezeichnung
- Integrin alpha3
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Hintergrund
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Description: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Gene: ITGA3
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Molekulargewicht
- 118 kDa
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Gen-ID
- 3675
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UniProt
- P26006
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Pathways
- CXCR4-mediated Signaling Events, Integrin Complex
Target
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