Interleukin 17a Antikörper (Internal Region)

Produktnummer ABIN6262537

Dieser Anti-Interleukin 17a Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Interleukin 17a in ELISA, WB, IHC, IF und ICC. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Interleukin 17a Antikörper (Internal Region) (ABIN6262537)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Interleukin 17a Antikörper

Bindungsspezifität: Internal Region

Spezifität: IL17A Antibody detects endogenous levels of total IL17A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL17A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:1500, IHC 1:50-1:200, IF/ICC 1:20-1:50, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-Interleukin 17a Antikörper (ABIN6262537)

Zhong, Gao, Zhou, Lin, Chen, Huang, Huang, Zhou, Huang, Nie, Liu, Chen, Zhou, Lv: "Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation." in: Oncotarget, Vol. 8, Issue 25, pp. 40486-40500, (2018) (PubMed).

Wang, Wei, Fan, Ding, Tian, Zhou, Cheng: "Progranulin Is Positively Associated with Intervertebral Disc Degeneration by Interaction with IL-10 and IL-17 Through TNF Pathways." in: Inflammation, (2018) (PubMed).

Yan, Yang, Han, Feng: "Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats." in: Molecular medicine reports, Vol. 14, Issue 2, pp. 1601-9, (2016) (PubMed).

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL17A

Hintergrund:

Description: Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).

Gene: IL17A

Molekulargewicht: 18kDa

Gen-ID: 3605

UniProt: Q16552