Fibronectin Antikörper (C-Term)

Produktnummer ABIN6261746

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Fibronectin in WB, IHC, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für Fibronectin Antikörper (C-Term) (ABIN6261746)

Target: Fibronectin

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibronectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Fibronectin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Fibronectin Antibody

Spezifität: Fibronectin Antibody detects endogenous levels of total Fibronectin.

Homologie: Pig,Bovine,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Fibronectin, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-Fibronectin Antikörper (ABIN6261746)

Yang, Zhou, Zhu, Fan, Liu, Duan, Tang, Shou, Zuo: "miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition." in: Journal of gastroenterology and hepatology, Vol. 32, Issue 12, pp. 1966-1974, (2018) (PubMed).

Xu, Sun, Fang, Song, Yan, Chen, Jiang, Fei, Zhao, Leboeuf, Li, Wang, Janin, Wang, Zhao: "JAM-A overexpression is related to disease progression in diffuse large B-cell lymphoma and downregulated by lenalidomide." in: Scientific reports, Vol. 7, Issue 1, pp. 7433, (2018) (PubMed).

Details zu Fibronectin

Target: Fibronectin

Hintergrund:

Description: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

Gene: FN1

Molekulargewicht: 263 kDa

Gen-ID: 2335

UniProt: P02751