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FGA Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-FGA-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, FGA in Proben von Human und Ratte zu detektieren.
Produktnummer ABIN6261717

Kurzübersicht für FGA Antikörper (C-Term) (ABIN6261717)

Target

Alle FGA Antikörper anzeigen
FGA (Fibrinogen alpha Chain (FGA))

Reaktivität

  • 58
  • 41
  • 28
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Ratte

Wirt

  • 75
  • 21
  • 6
  • 2
Kaninchen

Klonalität

  • 80
  • 24
Polyklonal

Konjugat

  • 59
  • 14
  • 11
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGA Antikörper ist unkonjugiert

Applikation

  • 83
  • 46
  • 27
  • 27
  • 21
  • 15
  • 13
  • 13
  • 10
  • 9
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 15
    • 10
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    FGA Antibody detects endogenous levels of total FGA.

    Homologie

    Chicken,Xenopus

    Aufreinigung

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human FGA, corresponding to a region within C-terminal amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C. Stable for 12 months from date of receipt.

    Haltbarkeit

    12 months
  • Target

    FGA (Fibrinogen alpha Chain (FGA))

    Andere Bezeichnung

    FGA

    Hintergrund

    Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

    Gene: FGA

    Molekulargewicht

    95 kDa

    Gen-ID

    2243

    UniProt

    P02671
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