FBXO22 Antikörper (Internal Region)
Kurzübersicht für FBXO22 Antikörper (Internal Region) (ABIN6261694)
Target
Alle FBXO22 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- Internal Region
- 
                                            Spezifität
- FBXO22 Antibody detects endogenous levels of total FBXO22.
- 
                                            Homologie
- Bovine,Sheep,Rabbit,Dog,Chicken
- 
                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            Immunogen
- A synthesized peptide derived from human FBXO22, corresponding to a region within the internal amino acids.
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - FBXO22 (F-Box Protein 22 (FBXO22))
- 
                                            Andere Bezeichnung
- FBXO22
- 
                                            Hintergrund
- 
                        Description: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function. Gene: FBXO22 
- 
                                            Molekulargewicht
- 45 kDa
- 
                                            Gen-ID
- 26263
- 
                                            UniProt
- Q8NEZ5
- 
                                            Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
 Target
- 
                    
 
                                     
                                     
                                    