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ETAA1 Antikörper (Internal Region)

ETAA1 Reaktivität: Human, Maus WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261612
  • Target Alle ETAA1 Produkte
    ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
    Bindungsspezifität
    • 1
    • 1
    Internal Region
    Reaktivität
    Human, Maus
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ETAA1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    ETAA1 Antibody detects endogenous levels of total ETAA1.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ETAA1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))
    Andere Bezeichnung
    ETAA1 (ETAA1 Produkte)
    Synonyme
    ETAA16 antikoerper, ETAA1 antikoerper, 5730466H23Rik antikoerper, AA672646 antikoerper, etaa1 antikoerper, MGC145507 antikoerper, MGC81344 antikoerper, RGD1560957 antikoerper, zgc:171518 antikoerper, ETAA1, ATR kinase activator antikoerper, Ewing tumor-associated antigen 1 antikoerper, Ewing tumor associated antigen 1 antikoerper, ETAA1, ATR kinase activator L homeolog antikoerper, ETAA1 antikoerper, Etaa1 antikoerper, etaa1 antikoerper, etaa1.L antikoerper
    Hintergrund

    Description: Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).

    Gene: ETAA1

    Molekulargewicht
    103 kDa
    Gen-ID
    54465
    UniProt
    Q9NY74
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