DOM3Z Antikörper (Internal Region)

Produktnummer ABIN6261355

Produktdetails anti-DOM3Z Antikörper

Target: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOM3Z Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: DOM3Z Antibody detects endogenous levels of total DOM3Z.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DOM3Z, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DOM3Z

Target: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Andere Bezeichnung: DXO (DOM3Z Produkte)

Synonyme: ng6 antikoerper, dom3l antikoerper, DXO antikoerper, DOM3L antikoerper, NG6 antikoerper, RAI1 antikoerper, decapping exoribonuclease antikoerper, dom-3 homolog Z (C. elegans) antikoerper, decapping exoribonuclease L homeolog antikoerper, DXO antikoerper, DOM3Z antikoerper, dxo antikoerper, dxo.L antikoerper, Dxo antikoerper

Hintergrund:

Description: Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).

Gene: DXO

Molekulargewicht: 45 kDa

Gen-ID: 1797

UniProt: O77932