DNAJA1 Antikörper (C-Term)

Produktnummer ABIN6261327

Der Kaninchen Polyklonal Anti-DNAJA1-Antikörper wurde für WB, ELISA, IHC, IF und ICC validiert. Er ist geeignet, DNAJA1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DNAJA1 Antikörper (C-Term) (ABIN6261327)

Target: DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-DNAJA1 Antikörper

Bindungsspezifität: C-Term

Spezifität: DNAJA1 Antibody detects endogenous levels of total DNAJA1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DNAJA1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DNAJA1

Target: DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))

Andere Bezeichnung: DNAJA1

Hintergrund:

Description: Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).

Gene: DNAJA1

Molekulargewicht: 44 kDa

Gen-ID: 3301

UniProt: P31689

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway