Cytochrome P450 2A6/7/13 Antikörper

Produktnummer ABIN6261195

Produktdetails

Target: Cytochrome P450 2A6/7/13

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: ELISA, Western Blotting (WB)

Spezifität: Cytochrome P450 2A6/7/13 Antibody detects endogenous levels of total Cytochrome P450 2A6/7/13

Kreuzreaktivität: Human

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 2A6/7/13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Antigendetails

Target: Cytochrome P450 2A6/7/13

Hintergrund:

Description: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Gene: CYP2A6

Molekulargewicht: 56 kDa

Gen-ID: 1548

UniProt: P11509, P20853, Q16696