Cofilin Antikörper (N-Term)
Kurzübersicht für Cofilin Antikörper (N-Term) (ABIN6260927)
Target
Alle Cofilin (CFL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Cofilin Antibody
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Spezifität
- Cofilin Antibody detects endogenous levels of total Cofilin.
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Homologie
- Pig,Bovine,Horse,Sheep,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Cofilin, corresponding to a region within N-terminal amino acids.
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Isotyp
- IgG
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anti-Cofilin 1 (CFL1) antibody
KO Validated CFL1 Reaktivität: Human WB, IF, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-166) antibodyCFL1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1A1 unconjugated
anti-Cofilin 1 (CFL1) (AA 3-161) antibodyCFL1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 70-98) antibodyCFL1 Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB23947 unconjugated
anti-Cofilin 1 (CFL1) (C-Term) antibodyCFL1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-100) antibodyCFL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 2-166) antibodyCFL1 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 4-32), (N-Term) antibodyCFL1 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20525 unconjugated
anti-Cofilin 1 (CFL1) (AA 4-32) antibodyCFL1 Reaktivität: Human, Maus WB, IHC, FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-166) antibodyCFL1 Reaktivität: Human WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal AT1C1 unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Andere Bezeichnung
- Cofilin
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Hintergrund
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Description: Binds to F-actin and exhibits pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
Gene: CFL1
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Molekulargewicht
- 19kDa
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Gen-ID
- 1072
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UniProt
- P23528
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Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Target
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