CNGB3 Antikörper (N-Term)

Produktnummer ABIN6260909

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNGB3 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNGB3 Antikörper (N-Term) (ABIN6260909)

Target: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNGB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CNGB3 Antikörper

Bindungsspezifität: N-Term

Spezifität: CNGB3 Antibody detects endogenous levels of total CNGB3.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNGB3, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CNGB3

Target: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Andere Bezeichnung: CNGB3

Hintergrund:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Gene: CNGB3

Molekulargewicht: 92 kDa

Gen-ID: 54714

UniProt: Q9NQW8