Centromere Protein C Pseudogene 1 (CENPCP1) (C-Term) Antikörper

Produktnummer ABIN6260752

Produktdetails

Target: Centromere Protein C Pseudogene 1 (CENPCP1)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Spezifität: CENPC1 Antibody detects endogenous levels of total CENPC1.

Homologie: Pig,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CENPC1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Antigendetails

Target: Centromere Protein C Pseudogene 1 (CENPCP1)

Andere Bezeichnung: CENPC (CENPCP1 Produkte)

Synonyme: CENPC antikoerper, CENPC1P1 antikoerper, CENPC2 antikoerper, centromere protein C pseudogene 1 antikoerper, CENPCP1 antikoerper

Hintergrund:

Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Gene: CENPC

Molekulargewicht: 106 kDa

Gen-ID: 1060

UniProt: Q03188