Centromere Protein C Pseudogene 1 (CENPCP1) (C-Term) Antikörper
Kurzübersicht für Centromere Protein C Pseudogene 1 (CENPCP1) (C-Term) Antikörper (ABIN6260752)
Target
Alle Centromere Protein C Pseudogene 1 (CENPCP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- CENPC1 Antibody detects endogenous levels of total CENPC1.
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Homologie
- Pig,Horse,Sheep,Rabbit,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human CENPC1, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Centromere Protein C Pseudogene 1 (CENPCP1)
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Andere Bezeichnung
- CENPC
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Hintergrund
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Description: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.
Gene: CENPC
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Molekulargewicht
- 106 kDa
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Gen-ID
- 1060
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UniProt
- Q03188
Target
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