CaMK2 beta/gamma Antikörper
Kurzübersicht für CaMK2 beta/gamma Antikörper (ABIN6260435)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- CaMKIIbeta/gamma Antibody detects endogenous levels of total CaMKIIbeta/gamma
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human CaMKIIbeta/gamma
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- CaMK2 beta/gamma
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Andere Bezeichnung
- CaMKIIbeta/gamma
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Hintergrund
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Description: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
Gene: CAMK2G
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Molekulargewicht
- 62kDa
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Gen-ID
- 818
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UniProt
- Q13555, Q13554
Target
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