CABP1 Antikörper (Internal Region)

Produktnummer ABIN6260388

Der Kaninchen-Polyklonal Anti-CABP1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von CABP1 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für CABP1 Antikörper (Internal Region) (ABIN6260388)

Target: CABP1 (Calcium Binding Protein 1 (CABP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CABP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CABP1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: CABP1 Antibody detects endogenous levels of total CABP1.

Homologie: Pig,Bovine,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CABP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CABP1

Target: CABP1 (Calcium Binding Protein 1 (CABP1))

Andere Bezeichnung: CABP1

Hintergrund:

Description: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed:14570872). Inhibits agonist-induced intracellular calcium signaling (PubMed:15980432). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941). Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels (PubMed:15895247). Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity).

Gene: CABP1

Molekulargewicht: 40 kDa

Gen-ID: 9478

UniProt: Q9NZU7

Pathways: Synaptic Membrane, Negative Regulation of Transporter Activity