PNPLA2 Antikörper (Internal Region)

Produktnummer ABIN6260110

Der Kaninchen Polyklonal anti-PNPLA2 Antikörper (ABIN6260110) detektiert spezifisch PNPLA2 in WB, ELISA, IHC, IF und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für PNPLA2 Antikörper (Internal Region) (ABIN6260110)

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNPLA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-PNPLA2 Antikörper

Bindungsspezifität: Internal Region

Spezifität: PNPLA2 Antibody detects endogenous levels of total PNPLA2.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PNPLA2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PNPLA2

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Andere Bezeichnung: PNPLA2

Hintergrund:

Description: Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

Gene: PNPLA2

Molekulargewicht: 54 kDa

Gen-ID: 57104

UniProt: Q96AD5