ARL3 Antikörper (C-Term)

Produktnummer ABIN6260040

Der Kaninchen Polyklonal Anti-ARL3-Antikörper wurde für WB validiert. Er ist geeignet, ARL3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ARL3 Antikörper (C-Term) (ABIN6260040)

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARL3 Antikörper

Bindungsspezifität: C-Term

Spezifität: ARL3 Antibody detects endogenous levels of total ARL3.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARL3, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ARL3

Target: ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

Andere Bezeichnung: ARL3

Hintergrund:

Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

Gene: ARL3

Molekulargewicht: 20 kDa

Gen-ID: 403

UniProt: P36405