ARHGAP22 Antikörper (C-Term)

Produktnummer ABIN6260025

Der Kaninchen Polyklonal Anti-ARHGAP22-Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, ARHGAP22 in Proben von Human und Maus zu detektieren.

Kurzübersicht für ARHGAP22 Antikörper (C-Term) (ABIN6260025)

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-ARHGAP22 Antikörper

Bindungsspezifität: C-Term

Spezifität: ARHGAP22 Antibody detects endogenous levels of total ARHGAP22.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARHGAP22, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ARHGAP22

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Andere Bezeichnung: ARHGAP22

Hintergrund:

Description: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).

Gene: ARHGAP22

Molekulargewicht: 77kDa

Gen-ID: 58504

UniProt: Q7Z5H3