GFER Antikörper (C-Term)

Produktnummer ABIN6259902

Produktdetails anti-GFER Antikörper

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFER Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: ALR Antibody detects endogenous levels of total ALR.

Homologie: Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ALR, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GFER

Target: GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))

Andere Bezeichnung: GFER (GFER Produkte)

Synonyme: ALR antikoerper, ERV1 antikoerper, HERV1 antikoerper, HPO antikoerper, HPO1 antikoerper, HPO2 antikoerper, HSS antikoerper, Alr antikoerper, growth factor, augmenter of liver regeneration antikoerper, growth factor, augmenter of liver regeneration L homeolog antikoerper, GFER antikoerper, Gfer antikoerper, gfer.L antikoerper

Hintergrund:

Description: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.

Gene: GFER

Molekulargewicht: 23-25 kDa

Gen-ID: 2671

UniProt: P55789

Pathways: SARS-CoV-2 Protein Interaktom