TADA2L Antikörper
Kurzübersicht für TADA2L Antikörper (ABIN6259764)
Target
Alle TADA2L (TADA2A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Spezifität
- ADA2L antibody detects endogenous levels of total ADA2L
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                                            Kreuzreaktivität
- Human, Affe, Maus, Ratte (Rattus)
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                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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                                            Immunogen
- A synthesized peptide derived from human ADA2L
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- WB: 1:500~1:3000, IF/ICC 1:100-1:500
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 1 mg/mL
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                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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                                            Haltbarkeit
- 12 months
 
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    - TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
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                                            Andere Bezeichnung
- ADA2L
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                                            Hintergrund
- 
                        Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376). Gene: TADA2A 
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                                            Molekulargewicht
- 47kDa
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                                            Gen-ID
- 6871
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                                            UniProt
- O75478
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                                            Pathways
- Chromatin Binding
 Target
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