Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TADA2L Antikörper

This anti-TADA2L antibody (ABIN6259764) is a Rabbit Polyclonal antibody detecting TADA2L in WB, ELISA, IF, ICC. Suitable for Human, Mouse, Rat, Monkey.
Produktnummer ABIN6259764

Kurzübersicht für TADA2L Antikörper (ABIN6259764)

Target

Alle TADA2L (TADA2A) Antikörper anzeigen
TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

Reaktivität

  • 41
  • 19
  • 19
  • 7
  • 6
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
Human, Maus, Ratte, Affe

Wirt

  • 38
  • 3
Kaninchen

Klonalität

  • 38
  • 3
Polyklonal

Konjugat

  • 29
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TADA2L Antikörper ist unkonjugiert

Applikation

  • 34
  • 18
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Spezifität

    ADA2L antibody detects endogenous levels of total ADA2L

    Kreuzreaktivität

    Human, Affe, Maus, Ratte (Rattus)

    Aufreinigung

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human ADA2L

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500~1:3000, IF/ICC 1:100-1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C.Stable for 12 months from date of receipt

    Haltbarkeit

    12 months
  • Target

    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

    Andere Bezeichnung

    ADA2L

    Hintergrund

    Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).

    Gene: TADA2A

    Molekulargewicht

    47kDa

    Gen-ID

    6871

    UniProt

    O75478

    Pathways

    Chromatin Binding
Sie sind hier:
Chat with us!