SRRM1 Antikörper (C-Term)

Produktnummer ABIN6259480

Dieses Anti-SRRM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SRRM1 in WB und ELISA. Geeignet für Maus und Human.

Kurzübersicht für SRRM1 Antikörper (C-Term) (ABIN6259480)

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SRRM1 Antikörper

Bindungsspezifität: C-Term

Spezifität: SRRM1 Antibody detects endogenous levels of total SRRM1.

Homologie: Pig,Bovine,Horse,Rabbit,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SRRM1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Andere Bezeichnung: SRRM1

Hintergrund:

Description: Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.

Gene: SRRM1

Molekulargewicht: 102 kDa

Gen-ID: 10250

UniProt: Q8IYB3