FIL1d Antikörper (Internal Region)

Produktnummer ABIN6259266

Der Kaninchen-Polyklonal Anti-FIL1d-Antikörper wurde für WB, ELISA, ICC und IF validiert. Er ist geeignet zum Nachweis von FIL1d in Proben aus Human und Maus. }

Kurzübersicht für FIL1d Antikörper (Internal Region) (ABIN6259266)

Target: FIL1d (Interleukin 1 delta (FIL1d))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIL1d Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-FIL1d Antikörper

Bindungsspezifität: Internal Region

Spezifität: IL1F5 Antibody detects endogenous levels of total IL1F5.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL1F5, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu FIL1d

Target: FIL1d (Interleukin 1 delta (FIL1d))

Andere Bezeichnung: IL36RN

Hintergrund:

Description: Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Gene: IL36RN

Molekulargewicht: 17 kDa

Gen-ID: 26525

UniProt: Q9UBH0