MORG1 Antikörper (Internal Region)

Produktnummer ABIN6259117

Dieses Anti-MORG1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MORG1 in WB, ELISA, IF und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MORG1 Antikörper (Internal Region) (ABIN6259117)

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MORG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-MORG1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: MORG1 Antibody detects endogenous levels of total MORG1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MORG1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MORG1

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Andere Bezeichnung: WDR83

Hintergrund:

Description: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Gene: WDR83

Molekulargewicht: 34 kDa

Gen-ID: 84292

UniProt: Q9BRX9