GNL3L Antikörper
Kurzübersicht für GNL3L Antikörper (ABIN6258968)
Target
Alle GNL3L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- GNL3L Antibody detects endogenous levels of total GNL3L
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Kreuzreaktivität
- Human
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide
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Isotyp
- IgG
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anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (Internal Region) antibody
GNL3L Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 102-130), (N-Term) antibodyGNL3L Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB28467 unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (N-Term) antibodyGNL3L Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen, Meerschweinchen, Pferd WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 71-120) antibodyGNL3L Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (N-Term) antibodyGNL3L Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (AA 102-130), (N-Term) antibodyGNL3L Reaktivität: Human WB, FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) (Internal Region) antibodyGNL3L Reaktivität: Human ELISA, WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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Andere Bezeichnung
- GNL3L
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Hintergrund
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Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Gene: GNL3L
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Molekulargewicht
- 66 kDa
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Gen-ID
- 54552
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UniProt
- Q9NVN8
Target
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