Manic Fringe Antikörper (Internal Region)
Kurzübersicht für Manic Fringe Antikörper (Internal Region) (ABIN6258883)
Target
Alle Manic Fringe (MFNG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- MFNG Antibody detects endogenous levels of total MFNG.
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Homologie
- Pig,Bovine,Horse,Dog
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human MFNG, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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anti-MFNG (MFNG) (AA 214-291) antibody
MFNG Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-MFNG (MFNG) (C-Term) antibodyMFNG Reaktivität: Human, Hund, Pferd, Meerschweinchen, Kaninchen, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) (AA 56-309) antibodyMFNG Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) antibodyMFNG Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) (AA 28-321) antibodyMFNG Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) (AA 221-321) antibodyMFNG Reaktivität: Maus ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) (AA 214-291) antibodyMFNG Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B11 unconjugated
anti-MFNG (MFNG) (AA 1-321) antibodyMFNG Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-MFNG (MFNG) (AA 211-260) antibodyMFNG Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Kaninchen, Fledermaus, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MFNG (MFNG) (AA 241-290) antibodyMFNG Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Schwein, Affe, Huhn, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- Manic Fringe (MFNG) (MFNG)
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Andere Bezeichnung
- MFNG
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Hintergrund
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Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).
Gene: MFNG
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Molekulargewicht
- 38 kDa
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Gen-ID
- 4242
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UniProt
- O00587
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Pathways
- Notch Signalweg
Target
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