TSEN54 Antikörper (Internal Region)

Produktnummer ABIN6258653

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TSEN54 in WB, IHC, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TSEN54 Antikörper (Internal Region) (ABIN6258653)

Target: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSEN54 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-TSEN54 Antikörper

Bindungsspezifität: Internal Region

Spezifität: TSEN54 Antibody detects endogenous levels of total TSEN54.

Homologie: Bovine

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TSEN54, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TSEN54

Target: TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Andere Bezeichnung: TSEN54

Hintergrund:

Description: Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Gene: TSEN54

Molekulargewicht: 59 kDa

Gen-ID: 283989

UniProt: Q7Z6J9

Pathways: Synaptic Membrane