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AOX1 Antikörper (Internal Region)

Der Kaninchen Polyklonal Anti-AOX1-Antikörper wurde für WB, ELISA, IHC, IF und ICC validiert. Er ist geeignet, AOX1 in Proben von Human, Ratte und Maus zu detektieren.
Produktnummer ABIN6258597

Kurzübersicht für AOX1 Antikörper (Internal Region) (ABIN6258597)

Target

Alle AOX1 Antikörper anzeigen
AOX1 (Aldehyde Oxidase 1 (AOX1))

Reaktivität

  • 29
  • 5
  • 4
  • 2
  • 2
  • 1
Human, Ratte, Maus

Wirt

  • 35
  • 1
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 15
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser AOX1 Antikörper ist unkonjugiert

Applikation

  • 22
  • 22
  • 10
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Spezifität

    AOX1 Antibody detects endogenous levels of total AOX1.

    Homologie

    Bovine,Horse

    Aufreinigung

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    Immunogen

    A synthesized peptide derived from human AOX1, corresponding to a region within the internal amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C. Stable for 12 months from date of receipt.

    Haltbarkeit

    12 months
  • Target

    AOX1 (Aldehyde Oxidase 1 (AOX1))

    Andere Bezeichnung

    AOX1

    Hintergrund

    Description: Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

    Gene: AOX1

    Molekulargewicht

    120 kDa

    Gen-ID

    316

    UniProt

    Q06278
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