SLC4A8/10 Antikörper
Kurzübersicht für SLC4A8/10 Antikörper (ABIN6258561)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- SLC4A8/10 Antibody detects endogenous levels of total SLC4A8/10
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500~1:1000, IF/ICC 1:100-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- SLC4A8/10 (Solute Carrier Family 4, Member 8/10 (SLC4A8/10))
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Andere Bezeichnung
- SLC4A8/10
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Hintergrund
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Description: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3- from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells. Also mediates lithium-dependent HCO3- cotransport. May be regulated by osmolarity.
Gene: SLC4A8
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Molekulargewicht
- 140 kDa
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Gen-ID
- 9498
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UniProt
- Q2Y0W8, Q6U841
Target
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