CCNB1IP1 Antikörper (Internal Region)

Produktnummer ABIN6258548

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCNB1IP1 in WB, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCNB1IP1 Antikörper (Internal Region) (ABIN6258548)

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCNB1IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-CCNB1IP1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: CCNB1IP1 Antibody detects endogenous levels of total CCNB1IP1.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCNB1IP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CCNB1IP1

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Andere Bezeichnung: CCNB1IP1

Hintergrund:

Description: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Gene: CCNB1IP1

Molekulargewicht: 32 kDa

Gen-ID: 57820

UniProt: Q9NPC3