CCNB1IP1 Antikörper (Internal Region)

Produktnummer ABIN6258548

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CCNB1IP1 in WB, ELISA, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CCNB1IP1 Antikörper (Internal Region) (ABIN6258548)

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCNB1IP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-CCNB1IP1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: CCNB1IP1 Antibody detects endogenous levels of total CCNB1IP1.

Homologie: Pig,Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CCNB1IP1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CCNB1IP1

Target: CCNB1IP1 (Cyclin B1 Interacting Protein 1 (CCNB1IP1))

Andere Bezeichnung: CCNB1IP1

Hintergrund:

Description: Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over (By similarity). Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Gene: CCNB1IP1

Molekulargewicht: 32 kDa

Gen-ID: 57820

UniProt: Q9NPC3