MARK1 Antikörper
Kurzübersicht für MARK1 Antikörper (ABIN6258271)
Target
Alle MARK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- MARK Antibody detects endogenous levels of total MARK
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Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide
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Isotyp
- IgG
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anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 560-700) antibody
MARK1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 6-40), (N-Term) antibodyMARK1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB8545 unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 643-674), (C-Term) antibodyMARK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB1272 unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 671-700), (C-Term) antibodyMARK1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB8547 unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (Internal Region) antibodyMARK1 Reaktivität: Human, Affe, Kaninchen, Fledermaus IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (N-Term) antibodyMARK1 Reaktivität: Human, Affe, Kaninchen, Pferd IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (N-Term) antibodyMARK1 Reaktivität: Human, Affe, Kaninchen, Fledermaus, Rind (Kuh), Hund IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (Center) antibodyMARK1 Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio) WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (AA 6-40) antibodyMARK1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) (Internal Region) antibodyMARK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500~1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
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Haltbarkeit
- 12 months
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- MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))
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Andere Bezeichnung
- MARK
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Hintergrund
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Description: Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Gene: MARK1
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Molekulargewicht
- 89 kDa
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Gen-ID
- 4139
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UniProt
- Q9P0L2, Q7KZI7, P27448, Q96L34
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Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
Target
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