NKIRAS2 Antikörper (C-Term)

Produktnummer ABIN6258238

Produktdetails anti-NKIRAS2 Antikörper

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKIRAS2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: NKIRAS2 Antibody detects endogenous levels of total NKIRAS2.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NKIRAS2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu NKIRAS2

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Andere Bezeichnung: NKIRAS2 (NKIRAS2 Produkte)

Synonyme: NKIRAS2 antikoerper, KBRAS2 antikoerper, kappaB-Ras2 antikoerper, zgc:92870 antikoerper, 2410003M04Rik antikoerper, 4930527H08Rik antikoerper, D630018G21Rik antikoerper, NFKB inhibitor interacting Ras like 2 antikoerper, NFKB inhibitor interacting Ras-like 2 antikoerper, NFKB inhibitor interacting Ras like 2 L homeolog antikoerper, NFKB inhibitor interacting Ras-like protein 2 antikoerper, NKIRAS2 antikoerper, Nkiras2 antikoerper, nkiras2 antikoerper, nkiras2.L antikoerper

Hintergrund:

Description: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

Gene: NKIRAS2

Molekulargewicht: 22 kDa

Gen-ID: 28511

UniProt: Q9NYR9