TRIO Antikörper (Internal Region)

Produktnummer ABIN6257891

Produktdetails anti-TRIO Antikörper

Target: TRIO (Triple Functional Domain Protein (TRIO))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: TRIO Antibody detects endogenous levels of total TRIO.

Homologie: Pig,Zebrafish,Horse,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TRIO, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TRIO

Target: TRIO (Triple Functional Domain Protein (TRIO))

Andere Bezeichnung: TRIO (TRIO Produkte)

Synonyme: ARHGEF23 antikoerper, tgat antikoerper, 6720464I07Rik antikoerper, AA408740 antikoerper, Solo antikoerper, si:dz230d15.1 antikoerper, trio Rho guanine nucleotide exchange factor antikoerper, triple functional domain (PTPRF interacting) antikoerper, trio Rho guanine nucleotide exchange factor b antikoerper, TRIO antikoerper, Trio antikoerper, triob antikoerper

Hintergrund:

Description: Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved in coordinating actin remodeling, which is necessary for cell migration and growth (PubMed:10341202). In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses (By similarity). May act as a regulator of adipogenesis (By similarity).

Gene: TRIO

Molekulargewicht: 31 kDa

Gen-ID: 7204

UniProt: O75962