HOPX Antikörper (C-Term)

Produktnummer ABIN6257752

Dieses Anti-HOPX-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HOPX in WB, ELISA und IHC. Geeignet für Human und Maus.

Kurzübersicht für HOPX Antikörper (C-Term) (ABIN6257752)

Target: HOPX (HOP Homeobox (HOPX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-HOPX Antikörper

Bindungsspezifität: C-Term

Spezifität: HOP Antibody detects endogenous levels of total HOP.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HOP, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: HOPX

Hintergrund:

Description: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (PubMed:27708256).

Gene: HOPX

Molekulargewicht: 8 kDa

Gen-ID: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation