Unc5c Antikörper (N-Term)

Produktnummer ABIN6257656

Der Kaninchen Polyklonal anti-Unc5c Antikörper (ABIN6257656) detektiert spezifisch Unc5c in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Unc5c Antikörper (N-Term) (ABIN6257656)

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Unc5c Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Unc5c Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: UNC5C Antibody

Spezifität: UNC5C Antibody detects endogenous levels of total UNC5C.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human UNC5C, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Unc5c

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Andere Bezeichnung: UNC5C

Hintergrund:

Description: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

Gene: UNC5C

Molekulargewicht: 66 kDa

Gen-ID: 8633

UniProt: O95185