LMTK3 Antikörper
Kurzübersicht für LMTK3 Antikörper (ABIN6257613)
Target
Alle LMTK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- LMTK3 Antibody detects endogenous levels of total LMTK3
-
Kreuzreaktivität
- Human, Maus
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500~1:1000, IF/ICC 1:100-1:500
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
-
Haltbarkeit
- 12 months
-
-
- LMTK3 (Lemur Tyrosine Kinase 3 (LMTK3))
-
Andere Bezeichnung
- LMTK3
-
Hintergrund
-
Description: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).
Gene: LMTK3
-
Molekulargewicht
- 40 kDa
-
UniProt
- Q96Q04
Target
-