ZFYVE19 Antikörper (Internal Region)
Kurzübersicht für ZFYVE19 Antikörper (Internal Region) (ABIN6257582)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- Internal Region
- 
                                            Spezifität
- ZFYVE19 Antibody detects endogenous levels of total ZFYVE19.
- 
                                            Homologie
- Horse,Rabbit,Dog
- 
                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            Immunogen
- A synthesized peptide derived from human ZFYVE19, corresponding to a region within the internal amino acids.
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))
- 
                                            Andere Bezeichnung
- ZFYVE19
- 
                                            Hintergrund
- 
                        Description: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. Gene: ZFYVE19 
- 
                                            Molekulargewicht
- 50 kDa
- 
                                            Gen-ID
- 84936
- 
                                            UniProt
- Q96K21
 Target
- 
                    
 
                                     
                                     
                                    