UBASH3A Antikörper (Internal Region)
Kurzübersicht für UBASH3A Antikörper (Internal Region) (ABIN6257504)
Target
Alle UBASH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Spezifität
- UBASH3A Antibody detects endogenous levels of total UBASH3A.
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Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human UBASH3A, corresponding to a region within the internal amino acids.
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Isotyp
- IgG
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anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 524-623) antibody
UBASH3A Reaktivität: Human ELISA, WB, IP Wirt: Maus Monoclonal 4D2 unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 287-455) antibodyUBASH3A Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) antibodyUBASH3A Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 470-482) antibodyVerified UBASH3A Reaktivität: Human ELISA, WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 313-340) antibodyUBASH3A Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB39533 unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (Internal Region) antibodyVerified UBASH3A Reaktivität: Human ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 1-451) antibodyUBASH3A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 524-623) antibodyUBASH3A Reaktivität: Human ELISA Wirt: Maus Monoclonal 1G6 unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 434-483) antibodyUBASH3A Reaktivität: Human, Rind (Kuh), Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) (AA 265-439) antibodyUBASH3A Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
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Andere Bezeichnung
- UBASH3A
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Hintergrund
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Description: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH . May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Gene: UBASH3A
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Molekulargewicht
- 74 kDa
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Gen-ID
- 53347
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UniProt
- P57075
Target
-
